ACTA Scientiarum Polonorum

The present work was undertaken to assess the radical scavenging and antioxidant properties of the mangosteen (Garcinia mangostana L.) pericarp extracts obtained by various solvents and its mixtures of different polarity. The extracts were evaluated by FRAP (Ferric reducing antioxidant power), ABTS (2,2-azinobis (3-ethylbenzothiazoline-6-sulfonicacid) diammonium salt], DPPH (1,1-diphenyl-2-picrylhydrazyl), reducing power and chelating ability on ferrous ion. Among the different extracts studied, ethyl acetate and acetone extract were observed to have good antioxidant activity. The FRAP values for ethyl acetate and acetone extract were 1.30 and 1.01 mM TEAC respectively at 1 mg/ml. The TEAC values for ABTS assay were 38.21 and 38.15 μM respectively at 100 μg/ml. The IC50 values to quench the DPPH free radicals of these two extracts were 30.01 μg/ml and 33.32 μg/ml, but the chelating assay was observed to be better in aqueous fractions of Acetone: water (80:20) at 12 mg/ml. From the above results it can be inferred that ethyl acetate and acetone were suitable solvent to extract the antioxidant compounds form mangosteen.