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original articleIssue 17 (4) 2018 pp. 399-407

Monika Duś-Żuchowska1, Joanna Bajerska2, Patrycja Krzyżanowska1, Agata Chmurzyńska2, Anna Miśkiewicz-Chotnicka1, Agata Muzsik2, Jarosław Walkowiak1

1Department of Pediatric Gastroenterology and Metabolic Diseases, Poznań University of Medical Sciences, Poland
2
Institute of Human Nutrition and Dietetics, Poznań University of Life Science, Poland

The Central European diet as an alternative to the Mediterranean diet in atherosclerosis prevention in postmenopausal obese women with a high risk of metabolic syndrome - a randomized nutrition-al trial

Abstract

Background. Metabolic syndrome (MS) is a powerful risk factor for atherosclerosis (AT). The crucial meth- od of minimizing the development of atherosclerosis and its clinical manifestations is lifestyle modifications, including following a healthy diet. The aim of the study was to check if the Central European Diet (CED) could be an alternative to the Mediterranean Diet (MED) in the prevention of AT in patients with a risk of MS.

Methods. The randomized, single-blind nutritional trial involved 144 obese women with a risk of MS. The subjects were randomly assigned to two groups and followed MED (n = 72) or CED (n = 72) for 16 weeks. The concentrations of high-sensitivity C-reactive protein (hs-CRP) and asymmetrical dimethylarginine (ADMA) were measured before and after nutritional intervention.

Results. In both studied groups, the concentrations of hs-CRP decreased significantly after the nutritional in- tervention (CED: p = 0.0107; MED: p = 0.0002). The ADMA levels were significantly lower after nutritional intervention in the CED group (p = 0.0187) but not in the MED group (p = 0.8354). However, the observed changes of hs-CRP concentrations (Δhs-CRP) and ADMA levels (ΔADMA) were not different between the groups (p = 0.5307 and p = 0.0905, respectively).

Conclusion. In the Central European post-menopausal obese population, a well-designed, energy-restricted diet with the use of food items traditional for the region (CED) could be a good alternative to MED in terms of AT prevention.

Keywords: metabolic syndrome, Mediterranean diet, Central European diet, atherosclerosis, hs-CRP, ADMA
pub/.pdf Full text available in english in Adobe Acrobat format:
http://www.food.actapol.net/issue4/volume/10_4_2018.pdf

http://dx.doi.org/10.17306/J.AFS.0593

For citation:

MLA Duś-Żuchowska, Monika, et al. "The Central European diet as an alternative to the Mediterranean diet in atherosclerosis prevention in postmenopausal obese women with a high risk of metabolic syndrome - a randomized nutrition-al trial." Acta Sci.Pol. Technol. Aliment. 17.4 (2018): 399-407. http://dx.doi.org/10.17306/J.AFS.0593
APA Duś-Żuchowska M., Bajerska J., Krzyżanowska P., Chmurzyńska A., Miśkiewicz-Chotnicka A., Muzsik A., Walkowiak J. (2018). The Central European diet as an alternative to the Mediterranean diet in atherosclerosis prevention in postmenopausal obese women with a high risk of metabolic syndrome - a randomized nutrition-al trial. Acta Sci.Pol. Technol. Aliment. 17 (4), 399-407 http://dx.doi.org/10.17306/J.AFS.0593
ISO 690 DUś-ŻUCHOWSKA, Monika, et al. The Central European diet as an alternative to the Mediterranean diet in atherosclerosis prevention in postmenopausal obese women with a high risk of metabolic syndrome - a randomized nutrition-al trial. Acta Sci.Pol. Technol. Aliment., 2018, 17.4: 399-407. http://dx.doi.org/10.17306/J.AFS.0593