Acta Scientiarum Polonorum Technologia Alimentaria

ISSN:1644-0730, e-ISSN:1898-9594

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original articleIssue 19 (1) 2020 pp. 123-131

Małgorzata Dobrzyńska, Juliusz Przysławski

Department of Bromatology, Poznan University of Medical Sciences, Poland

The relationship between serum uric acid concentration and cardiovascular risk factors in normotensive postmenopausal women with dyslipidemia

Abstract

Background. According to the latest recommendation for patients with hyperuricemia and high cardiovascular risk, the serum uric acid (SUA) concentration should be lower than 5 mg/dL (<298 μmol/L). Additionally, studies have shown that SUA concentration in participants with hyperuricemia correlates with some dietary factors. The aim of this study was to assess the relationship between SUA concentration and some cardiovascular risk factors.

Material and methods. Fifty-six postmenopausal women with dyslipidemia and without hypertension were assigned to 2 groups based on SUA concentration. The first group consisted of women with a SUA concentration ≥5 mg/dL and without gout, and the second group comprised women with a SUA concentration <5 mg/dL. Anthropometric parameters, nutrition, structure of consumption, dietary potential renal acid load (PRAL), lipid profile parameters and blood pressure were evaluated.

Results. Postmenopausal women with a SUA ≥5 mg/dL had statistically significant higher values of serum triglyceride (TG) concentration, waist-to-hip ratio (WHR) and diastolic blood pressure than women with a SUA concentration <5 mg/dL. Analysis of nutrition showed statistically significant differences between the groups in the intake of starch, saturated and polyunsaturated fatty acids, cholesterol and vitamin E. Additionally, we observed a correlation between PRAL value and SUA. The structure of consumption between the groups was varied.

Conclusion. SUA concentration ≥5 mg/dL may increase the cardiovascular risk. The association observed between PRAL and SUA can be used to evaluate diet.

Keywords: uric acid, cardiovascular disease, postmenopausal, nutrition, dietary potential renal acid load
pub/.pdf Full text available in english in Adobe Acrobat format:
https://www.food.actapol.net/volume19/issue1/11_1_2020.pdf

https://doi.org/10.17306/J.AFS.2020.0740

For citation:

MLA Dobrzyńska, Małgorzata, and Juliusz Przysławski. "The relationship between serum uric acid concentration and cardiovascular risk factors in normotensive postmenopausal women with dyslipidemia." Acta Sci.Pol. Technol. Aliment. 19.1 (2020): 123-131. https://doi.org/10.17306/J.AFS.2020.0740
APA Dobrzyńska M., Przysławski J. (2020). The relationship between serum uric acid concentration and cardiovascular risk factors in normotensive postmenopausal women with dyslipidemia. Acta Sci.Pol. Technol. Aliment. 19 (1), 123-131 https://doi.org/10.17306/J.AFS.2020.0740
ISO 690 DOBRZYńSKA, Małgorzata, PRZYSłAWSKI, Juliusz. The relationship between serum uric acid concentration and cardiovascular risk factors in normotensive postmenopausal women with dyslipidemia. Acta Sci.Pol. Technol. Aliment., 2020, 19.1: 123-131. https://doi.org/10.17306/J.AFS.2020.0740